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Mesothelioma Cancer Symptoms & Diagnosis

February 22nd, 2008 admin Posted in Mesothelioma Cancer No Comments »

What are the symptoms of Mesothelioma Cancer?

About 15% of Mesothelioma cases are found in the early stages, before the cancer has spread to nearby lymph nodes or elsewhere. The 5 year survival rate for people with Mesothelioma is 50% if there is no evidence of cancer in lymph nodes at the time of surgery. Unfortunately, in most cases, the spread of cancer has already occurred even if not detected by current medical tests. When all Mesothelioma stages are considered together, the 5 year survival rate is only about 14%. Many early Mesothelioma are diagnosed incidentally - they are found as a result of tests that are done for an unrelated medical condition. Although Mesothelioma does not cause any symptoms until it has spread too far to be cured, symptoms do occur in some patients with early Mesothelioma . Prompt attention to symptoms, leading to early diagnosis and treatment can result in a cure for some patients. For others, prompt attention to symptoms can improve the likelihood that treatment can extend their life and relieve many of their symptoms.

Common signs and symptoms of Mesothelioma include:

  • A cough that does not go away
  • Chest pain, often aggravated by deep breathing
  • Hoarseness
  • Weight loss and loss of appetite
  • Bloody or rust-colored sputum (spit or phlegm)
  • Shortness of breath
  • Fever without a known reason
  • Recurring infections such as bronchitis and pneumonia
  • New onset of wheezing
  • When Mesothelioma spreads to distant organs, it may cause:
  • Bone pain
  • Neurologic changes (such as weakness or numbness of a limb, dizziness)
  • Jaundice (yellow coloring of the skin and eyes)
  • Masses near the surface of the body, due to cancer spreading to the skin or to lymph nodes (collection of immune system cells) in the neck or above the collarbone.

A. Pleural Mesothelioma Symptoms
Some of the symptoms of pleural mesothelioma (mesothelioma cancer of the lung lining) include:

  • pain in the lower back or the side of the chest
  • shortness of breath
  • a persistent cough
  • difficulty swallowing food
  • fever and sweating
  • fatigue
  • weight loss.

These symptoms are also common to many minor ailments and, therefore, may not cause a doctor to suspect mesothelioma.

Pleural Effusion-fluid in the Lungs. One of the most common and specific symptoms of pleural mesothelioma is the accumulation of fluid between the lungs and chest cavity. This generally causes shortness of breath, and requires a doctor to drain the fluid, called fine-needle aspiration, to make breathing easier and relieve chest pain. This symptom is more unique to mesothelioma, making it more likely that you may have the disease.

B. Peritoneal Mesothelioma Symptoms
Symptoms of peritoneal mesothelioma (abdominal mesothelioma - mesothelioma of the lining of the stomach) include:

  •  stomach pain
  • nausea and vomiting
  • weight loss.

Like pleural mesothelioma, these symptoms are also common to many minor ailments and, therefore, may not cause a doctor to suspect mesothelioma.

How is Mesothelioma Cancer diagnosed?

Mesothelioma is diagnosed by pathological examination from a biopsy. Tissue is removed, placed under the microscope, and a pathologist makes a definitive diagnosis, and issues a pathology report. This is the end of a process that usually begins with symptoms that send most people to the doctor: a fluid build-up around the lungs (pleural effusions), shortness of breath, pain in the chest, or pain or swelling in the abdomen. The doctor may order an x-ray or CT scan of the chest or abdomen. If further examination is warranted, the following tests may be done:

  • Thoracoscopy - For pleural mesothelioma the doctor may look inside the chest cavity with a special instrument called a thoracoscope. A cut will be made through the chest wall and the thoracoscope will be put into the chest between two ribs. This test is usually done in a hospital with a local anesthetic or painkiller. If fluid has collected in your chest, your doctor may drain the fluid out of your body by putting a needle into your chest and use gentle suction to remove the fluid. This is called thoracentesis.
  • Peritoneoscopy - For peritoneal mesothelioma the doctor may also look inside the abdomen with a special tool called a peritoneoscope. The peritoneoscope is put into an opening made in the abdomen. This test is usually done in the hospital under a local anesthetic.If fluid has collected in your abdomen, your doctor may drain the fluid out of your body by putting a needle into your abdomen and using gentle suction to remove the fluid. This process is called paracentesis.
  • Biopsy - If abnormal tissue is found, the doctor will need to cut out a small piece and have it looked at under a microscope. This is usually done during the thoracoscopy or peritoneoscopy, but can be done during surgery.
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What is Mesothelioma Cancer?

February 17th, 2008 admin Posted in Mesothelioma Cancer No Comments »

What is Mesothelioma Cancer?

Mesothelioma is a cancer that is deadly, found in people that have had exposure to asbestos. Asbestos finds its victims as it floats through the air. These airborne particles are taken into the body by unsuspecting people by simply breathing. They then get trapped within the thin lining that is inside the lungs. There is an estimated minimum of 2,500 individuals per year that are diagnosed with this deadly cancer.

Although asbestos has been banned in the 1970s, there is still a severe risk today for ingesting these tiny particles. Mesothelioma has a long term inactive time. In some cases, it can be stagnant for up to 50 years before the effects are acknowledged. A vast majority of the sufferers of mesothelioma were exposed to the asbestos while working in construction jobs, doing brake work to elevators, and even in power plants and shipyards. The main timeframe for ingesting the asbestos has been narrowed down to the 1950’s through the 1970’s.

Asbestos continues to be a serious issue for workers within the industries themselves. Among probably the highest level of exposure to asbestos will be done by workers that remodel old buildings that are contaminated with asbestos. It has been predicted that there will be an increase in the number of people that are diagnosed with mesothelioma within the U.S. for at a bear minimum of 10 to 20 more years.

The fibers are extremely toxic for not only the individuals that are directly exposed but the individuals that come in contact with them as well. These tricky particles are able to cling to the exposed individuals clothing, thus being transported into a persons home. They can then be transferred by a hug or during laundering. In a chain reaction so to speak exposing everyone within a household to this deadly fiber.

Asbestos continues to be a serious issue for workers within the industries themselves. Among probably the highest level of exposure to asbestos will be done by workers that remodel old buildings that are contaminated with asbestos. It has been predicted that there will be an increase in the number of people that are diagnosed with mesothelioma within the U.S. for at a bear minimum of 10 to 20 more years.

The fibers are extremely toxic for not only the individuals that are directly exposed but the individuals that come in contact with them as well. These tricky particles are able to cling to the exposed individuals clothing, thus being transported into a persons home. They can then be transferred by a hug or during laundering. In a chain reaction so to speak exposing everyone within a household to this deadly fiber.

What Causes Mesothelioma Cancer?

Asbestos - The major known cause of mesothelioma is exposure to asbestos. A known history of asbestos exposure is present in 70-80% of all cases of mesothelioma. Asbestos likely causes cancer by physically irritating the cells. When asbestos fibers are breathed in, they reach the ends of the small airways and penetrate into the pleura (lining of the lung). These fibers may then injure mesothelial cells of the pleura and eventually cause mesothelioma.

The risk of developing mesothelioma rises with the quantity of asbestos exposure. However, genetic factors also play a role in determining who develops the condition. This is probably the reason why all people exposed to high levels of asbestos do not develop mesothelioma.

Smoking - Although smoking has not been associated with the development of mesothelioma, the combination of smoking and asbestos exposure significantly increases a person’s risk of developing pleural mesothelioma.

Other Causes - Mesothelioma also has been linked to the following:

  • Radiation: Mesothelioma has been reported to occur in few people following exposure to therapeutic radiation using thorium dioxide (Thorotrast).
  • Zeolite: Zeolite is a silicate mineral (chemically related to asbestos) commonly found in the soil of the Anatoli region of Turkey. A few cases of mesothelioma reported from this region may have been caused by zeolite.
  • Simian virus 40 (SV40): The role of SV40 in the development of mesothelioma has also been suggested. This virus has been identified in human mesothelioma cells. In studies conducted in animals, it has been shown to induce the development of mesothelioma. However, further research is needed to confirm the link.
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